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(Mixing drugs)

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Question: should there be a mention of mixing drugs (e.g. barbituates and alcohol)? Or should that be a separate article? Meelar (talk) 23:24, Oct 15, 2004 (UTC)

"Key points to prevent overdose on illicit drugs"

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Sources, anyone?
Brandonm2 17:20, 23 August 2006 (UTC)[reply]

"No mention of overdose risk and potency risk?"

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I am sort of getting the impression that there should be more mention of the dangers of Heroin in this page as many people have died because of the drug.
—Preceding unsigned comment added by Bardock the Mexican (talk • contribs) 20:22, 5 October 2006

how about abstainence?

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Instead of "try a low dose first" or "be aware of periods of low tolerance..." How about simply "Don't use Illicit drugs." rawr
—Preceding unsigned comment added by 24.60.253.36 (talk) 03:57, 25 October 2006

  • Agreed... Not using drugs in a manner which is not part of the regimen prescribed by a doctor seems like the best way....
    —Preceding unsigned comment added by 71.229.26.210 (talk) 01:38, 15 March 2007
  • Please sign your posts. How can you say that abstinence from illicit drugs prevent all overdoses? And if a person is abstinent from a drug, how is overdose of that drug even an issue? The prevention methods are valid, they only need a little rewriting (Wikipedia is not a how-to guide) --GSchjetne (talk) 19:32, 19 August 2008 (UTC)[reply]
  • People are going to use illicit drugs and its not the job of an encyclopedia to tell them 'not to use illicit drugs'. If were going to discuss overdose, harm reduction is by far a better policy than signing articles, with 'don't use drugs'. Obviously you can say all drug use, esp. illicit use is dangerous because: your not a doctor, you don't know the product and purity, etc. -ZCM
    —Preceding unsigned comment added by 66.191.120.105 (talk) 07:13, 26 November 2008

Introduction

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This article does not have a proper introductory paragraph. Could somebody add one? --  Denelson83  06:38, 7 June 2007 (UTC)[reply]

Mcasa074 (talk) 23:49, 13 September 2019 (UTC)Could the introduction contain a brief mention of each section?[reply]

"Overdose vs. drug-drug interactions

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Added reference. Drug-drug interactions can contribute to an 'overdose', but are not necessarily the same as an overdose. 124.169.111.219 (talk) 02:46, 8 February 2008 (UTC)[reply]

Classical Conditioning

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The interpretation of the rules of classical conditioning are incorrect in this article. While the environment would evoke the compensatory response much like the bell caused Pavlov's dogs to salivate, the unconditioned response would still come about from the unconditioned stimulus, just like food would still cause the dogs to salivate, regardless of their response to the bell. Thus, new environment or old, the compensatory response would be the same. I suspect the research article was interpreted incorrectly. —Preceding unsigned comment added by 68.49.136.206 (talk) 20:22, 11 July 2008 (UTC)[reply]

  • ---I'm not an expert on conditioning, but from what I've read the original writer is likely correct. Just because heroin itself elicits a conditioned response (like the release of mu-antagonist peptides), are you saying that the environment can't be responsible for some similar conditioned response and thus allow an 'overdose' to occur in a new environment by reducing (but not eliminating) the total conditioned response. Although the 'heroin' compensatory response would still be present in the new environment, the 'place where I get high' response would be absent (similarly with a change in the way one injects, or another change in the using ritual). See the The Consumers Union Report on Licit and Illicit Drugs, Ch. 12 'The "heroin overdose" mystery and other occupational hazards of addiction' at the Schaffer Drug Policy Library at http://druglibrary.net/schaffer/Library/studies/cu/cumenu.htm. -ZCM

—Preceding unsigned comment added by 66.191.120.105 (talk) 07:07, 26 November 2008 (UTC)[reply]

Suggested addition

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Might I suggest a link to the NTA's booklet "Overdose - everything you need to know' [1] This deals with overdoses (symptoms, myths and what-to-do) in a non-judgmental fashion. —Preceding unsigned comment added by 80.168.14.130 (talk) 16:17, 27 October 2008 (UTC)[reply]

Toxin vs. Drug

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Carbon Monoxide is a poison or toxin, not a drug (has no medical/recreational value) it doesn't belong under the antidotes/treatment section. -ZCM —Preceding unsigned comment added by 66.191.120.105 (talk) 07:19, 26 November 2008 (UTC)[reply]

Okay and feel free to fix this.--Doc James (talk · contribs · email) 22:44, 5 February 2009 (UTC)[reply]

Overdose caused by adulterated drugs

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Re: this edit
Possible source could be found here:

http://books.google.ca/books?id=eWtKrL-PRUcC&pg=PA52&lpg=PA52&dq=%22overdose+caused+by+adulterated+drugs%22&source=bl&ots=OB5TijbXpV&sig=rog1GpPW-ri9-v-ErmEsQkc_bz8&hl=en&ei=LnHmSc6hFpq4tgPqwrzvAQ&sa=X&oi=book_result&ct=result&resnum=4

-- OlEnglish (Talk) 23:49, 15 April 2009 (UTC)[reply]

"Homicide" drug cocktail

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Someone added to the Dab Homicide

* Homicide (drug), a street drug composed of heroin, scopolamine, dextromethorphan, cocaine, and thiamine, known for lethal toxicity and resistance to anti-overdose drug naloxone

which cannot stay there bcz:

  1. The red/blue-link combo must have a single blue link
  2. The blue-link'd article must have some information on the name in the red link (and those do not, nor does naloxone
  3. There must be articles that actually link via the red link

(Nor on any other Dab pg in that form, since Dab entries do not exist to provide info, but to get users to other WP articles.) Something related to Drug overdose seems like the most likely place, short of an article on drug-cocktails involving street drugs -- assuming, of course, verifiability; a blue link to such a page could appear in an entry at Homicide along the lines of

* Homicide, street-drug cocktail known for overdose risk

or (if there is reason to link to the section from at least one existing article)

* Homicide (drug), street-drug cocktail known for overdose risk

Or something that a more suitable subject-area editor than i will come up with.
--Jerzy•t 05:47, 9 November 2009 (UTC)[reply]

An overview of antidotes

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We should probably provide a brief overview. Here is a good paper. Betten DP, Vohra RB, Cook MD, Matteucci MJ, Clark RF (2006). "Antidote use in the critically ill poisoned patient". J Intensive Care Med. 21 (5): 255–77. doi:10.1177/0885066606290386. PMID 16946442.{{cite journal}}: CS1 maint: multiple names: authors list (link) Doc James (talk · contribs · email) 20:38, 17 January 2010 (UTC)[reply]


Inclusion of Marijuana

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Marijuana should not be included in the list of "drugs or toxins frequently involved in overdose and death." There have been no recorded cases of Marijuana overdose. I've removed it from the list. 68.49.92.69 (talk) 05:05, 8 March 2010 (UTC)[reply]

Thank you. Doc James (talk · contribs · email) 06:01, 8 March 2010 (UTC)[reply]

Listing classes of medications

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It is sufficient to list the classes of toxins here. List all the exact benzos or narcotics is not required. Doc James (talk · contribs · email) 13:02, 19 January 2011 (UTC)[reply]

In the media

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While not a press mention, this article is featured on-screen during the first episode of the U.S. version of the Wilfred television series, aired on June 23, 2011. A lead character consults the article while (unsuccessfully) trying to commit suicide by taking an entire bottle of pills mixed into a smoothie. - Dravecky (talk) 10:53, 29 June 2011 (UTC)[reply]

Number and breakdown of unintentional yearly U.S. drug overdose deaths

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I may add more references here as I find them. I don't know if I will have time to integrate the info into the article. Feel free.

One of the references already in the article gives a total for unintentional poisoning deaths:

"Unintentional poisoning deaths. Number of deaths: 33,041. Deaths per 100,000 population: 10.7"
"In 2011, 33,071 (80%) of the 41,340 drug overdose deaths in the United States were unintentional, 5,298 (12.8%) were of suicidal intent, 80 (0.2%) were homicides, and 2,891 (7%) were of undetermined intent."
"In 2010, there were 38 329 drug overdose deaths in the United States; most (22 134; 57.7%) involved pharmaceuticals; 9429 (24.6%) involved only unspecified drugs. Of the pharmaceutical-related overdose deaths, 16 451 (74.3%) were unintentional, 3780 (17.1%) were suicides, and 1868 (8.4%) were of undetermined intent."
Chart: "Specific Drug Involvement in Pharmaceutical Overdose Deaths, United States, 2010":
http://jama.jamanetwork.com/data/Journals/JAMA/926413/jld130001t1.png

2014 numbers

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"During 2014, 47,055 drug overdose deaths occurred in the United States. Since 2000, the age-adjusted drug overdose death rate has more than doubled, from 6.2 per 100,000 persons in 2000 to 14.7 per 100,000 in 2014." - Increases in Drug and Opioid Overdose Deaths — United States, 2000–2014. Morbidity and Mortality Weekly Report. January 1, 2016 article. --Timeshifter (talk) 20:17, 1 July 2016 (UTC)[reply]

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Updated charts. May need to refresh your cache to see 2015 columns

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--Timeshifter (talk) 15:55, 29 October 2017 (UTC)[reply]

Reference cited is an opinion piece

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"It is very rare for a victim of an overdose to have consumed just one drug. Most overdoses occur when drugs are ingested in combination with alcohol.[24]" The cited article is an opinion piece, with no real factual supports listed pertinent to the current conversation. As it is from twenty-two years ago, before the current crest of this opiod crisis and prior to the adulteration of street opiods with the quantity of synthetic fentanyls, etc, it is not a provable factual statement that "most overdoses occur when drugs are ingested in combination with alcohol". Cited reference: https://www.peele.net/lib/heroinoverdose.html 216.68.236.9 (talk) 17:45, 22 January 2020 (UTC)[reply]

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